Survey Reveals Gaps in Needs of Patients with Ovarian Cancer

June 2, 2017 7:23 pm

A recent survey of patients with ovarian cancer has found that many of them are uncertain of what to expect after diagnosis, and this uncertainty can be challenging. More than half of the patients (53 percent) surveyed indicated that the … Read more

FDA Approves Cancer Drug for a Biomarker Not a Tissue

May 31, 2017 8:26 pm

Colon, pancreatic, stomach, or ovarian cancer; it increasingly shouldn’t matter. In an era of precision medicine, the treatment approach should reflect the genetic makeup of the person’s tumor and the presence or absence of key biomarkers.

That ethos was set … Read more

New Study: Improve Chemotherapy Strategies for Ovarian Cancer

May 24, 2017 6:46 pm

Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate all of the cancer cells because they have spread throughout the abdomen. Surgery is therefore followed … Read more

ImmunoGen Drug Moving Ahead In Single-Agent, Combination Trials

May 19, 2017 7:13 pm

Latest results from a mid-stage trial of ImmunoGen Inc’s experimental antibody-drug conjugate show that it shrinks or stabilizes tumors in nearly half of advanced ovarian cancer patients with at least medium levels of a key biomarker whose disease has become Read more

Ovarian Cancer: Clot Risk High in All Phases of Treatment

May 17, 2017 7:43 pm

One in four women with ovarian cancer develop blood clots, and over 10% develop clots during neoadjuvant chemotherapy given before surgery, according to a study published online May 5 in Obstetrics & Gynecology.

Past efforts at preventing blood clots in … Read more

Ovarian Cancer Patients Actively Seeking PARP Inhibitor Therapy, Expert Says

May 15, 2017 5:19 pm

In the treatment of advanced ovarian cancer, PARP inhibitors, including olaparib (Lynparza), rucaparib (Rubraca), and niraparib (Zejula), are stealing the limelight, explains Dennis Scribner, MD.

In an interview with Targeted Oncology, Scribner, a gynecologic oncologist at Arizona Oncology, discussed … Read more

Ovarian/Breast Cancer Vaccine Research Looks To Establish Therapeutic Efficacy

May 12, 2017 3:49 pm

Targeting the immune system to fight cancer is not new: in 1891, New York bone sarcoma surgeon William B. Coley injected a patient with an inoperable malignant tumor with streptococcal organisms. His theory was that the resulting severe bacterial infection, … Read more

J&J Loses $110 Million Verdict Over Talc Cancer-Link Claim

May 10, 2017 6:46 pm

Johnson & Johnson was ordered by a St. Louis jury to pay more than $110 million to a Virginia woman who blamed her ovarian cancer on the company’s talcum products.

Imerys Talc America, which provided the talc to J&J, was … Read more

Adding Bevacizumab to Chemo May Prolong Survival

May 8, 2017 8:58 pm

Adding bevacizumab to platinum-based chemotherapy may improve survival among women with recurrent ovarian cancer, according to a study published in Lancet Oncology.1

Bevacizumab is emerging as an effective strategy as a first-line or maintenance therapy for recurrent ovarian … Read more

Combination Therapy Could Provide New Treatment Option For Ovarian Cancer

May 5, 2017 4:05 pm

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer — the most common subtype of ovarian cancer — after standard treatment with the chemotherapy drug carboplatin.

Preclinical research from … Read more

Ending a Dry Spell of Years Without Treatment for Ovarian Cancer

May 3, 2017 7:04 pm

Teri Woodhull is decidedly proactive. A strong family history of breast cancer led her to undergo a preventive bilateral mastectomy at age 30. Seventeen years later, she was diagnosed with stage 3b high-grade serous epithelial ovarian cancer.

“I do have … Read more

Study Supports Risk-Reducing Salpingo-Oophorectomy

April 24, 2017 12:25 am

A large hereditary cancer study supports National Comprehensive Cancer Network guidance to consider risk-reducing salpingo-oophorectomy (RRSO) between ages 45 and 50 years for women with BRIP1, RAD51C, or RAD51D mutations, Lydia Usha, MD, said at the annual meeting of the … Read more

Recruitment Begins for World’s First Ovarian Cancer Vaccine Trial

April 21, 2017 6:16 pm

UConn Health is beginning to recruit patients for the world’s first personalized genomics-driven ovarian cancer vaccine clinical trial. The goal: to prevent an often deadly relapse of the disease in women diagnosed at advanced stages.

The pioneering injectable vaccine OncoImmunome … Read more

Hypertension Linked to Better Outcomes for Subset of Ovarian Cancer Patients

April 20, 2017 1:54 am

Hypertension, or high blood pressure, may come with a plus side, at least for a subset of women with ovarian cancer. New research from epidemiologists at Roswell Park Cancer Institute, published in the journal Cancer Causes & Control, provides evidence … Read more

PARP Inhibitor Approvals Offer Ovarian Cancer Patients New Hope

April 18, 2017 5:20 pm

The ovarian cancer treatment paradigm underwent another transformation near the end of 2016 with the FDA approval of the PARP inhibitor rucaparib (Rubraca) for patients with BRCA-positive advanced ovarian cancer who have received at least 2 prior lines of … Read more

Expert Discusses Surgery’s Evolving Role in Ovarian Cancer

April 14, 2017 7:03 pm

Surgical resection continues to be useful in treating patients with advanced ovarian cancer, according to Shana Wingo, M.D.

Whether a treatment plan includes cytoreduction upfront or neoadjuvant chemotherapy, patients with advanced disease are likely to benefit from surgical approaches that … Read more

New Imaging Test Can Show Key Enzyme in Ovarian Cancer to Help Guide Treatment

April 3, 2017 9:09 pm

A new imaging test may provide the ability to identify ovarian cancer patients who are candidates for an emerging treatment that targets a key enzyme cancer cells need to survive. Currently, epithelial ovarian cancer patients with BRCA1 mutations are considered … Read more