Tag: Clear Cell

Wistar Scientists Identify New Therapeutic Target in Ovarian Cancer Subtype With Poor Prognosis. Ovarian clear cell carcinomas with ARID1A mutations are sensitive to inhibition of the IRE1a-XBP1 stress response pathway in preclinical models.

September 21, 2021 5:12 pm

By Wistar Institute

Newswise — PHILADELPHIA — (Sept. 21, 2021) — Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered … Read more

Drug May Help Overcome Chemo Resistance in Ovarian Cancer

April 17, 2020 10:00 am

Scientists from Mater Research – The University of Queensland, have discovered they can overcome chemotherapy resistance in an ovarian cancer subtype by using low doses of a drug which slows cell growth.

Led by Professor John Hooper, the TRI-based Mater … Read more