OCRA Issues Consensus Statement Calling for Consideration of Fallopian Tube Removal to Prevent Ovarian Cancer

February 3, 2023 2:16 pm

by Jo Cavallo

The UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) has shown that general population screening did not significantly reduce ovarian and tubal cancer deaths, and the researchers concluded that such screening cannot be recommended. The findings from … Read more

Study yields insights into patient perceptions of cancer clinical trial benefits, burdens

February 1, 2023 2:09 pm

by Jennifer Byrne

Patient withdrawal from cancer clinical trials can result in systematic bias, insufficiently powered studies and a loss of valuable scientific knowledge, according to a study in JAMA Network Open.

Although increased attention has been paid to … Read more

Ovarian Cancer Tied to Bacteria Colonization of Microbiome

January 18, 2023 10:34 am

A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic’s Center for Individualized Medicine. The discovery, published in Scientific Reports, strengthens evidence that the … Read more

Genetic Test Identifies Ovarian Cancer Patients Likely To Benefit From PARP Inhibitors

January 12, 2023 9:58 am

A genetic test developed in a study at the University of Helsinki and Helsinki University Hospital identifies ovarian cancer patients who benefit from PARP inhibitors, a treatment option.

Since the therapy is associated with potential serious side-effects, it is important … Read more

Racial, ethnic minority groups lack representation in OB/GYN trials

January 4, 2023 10:23 am

by Kalie VanDewater

Reporting of race and ethnicity data and representation of different racial and ethnic populations in OB/GYN clinical trials are subpar, although improvement is possible, according to findings published in JAMA Surgery.

“Although trial results inform policies … Read more

Guideline addresses use of integrative therapies for cancer-related pain management

November 30, 2022 3:07 pm

by Jennifer Byrne

A new clinical practice guideline jointly published by ASCO and Society for Integrative Oncology addresses the potential role of integrative pain management techniques in management of cancer-related pain in adults.

“Patients with cancer, as well as cancer … Read more

Race, Ethnicity ‘Notably Underreported’ in Publicly Accessible Databases of Gynecologic Cancer Trials

November 29, 2022 2:29 pm

by Nicolas Wrigley

Findings from a recent 30-year analysis of more than 1,000 gynecologic cancer trials strongly suggest that reporting race and ethnicity must be a required part of clinical research to improve diversity, according to a group of researchers.Read more

Machine learning model builds on imaging methods to better detect ovarian lesions

November 29, 2022 11:37 am
by Beth Miller
(From left) The top row shows an ultrasound image of a malignant lesion, the blood oxygen saturation, and hemoglobin concentration. The bottom row is an ultrasound image of a benign lesion, the blood oxygen saturation, and hemoglobin
Read more

Penn Study Illuminates Why Cancers Caused by BRCA Mutations Recur

November 10, 2022 11:36 am

Findings uncover possible drivers of recurrent breast and ovarian cancers among women carrying high-risk genetic mutations, pointing to methods to more effectively treat disease

PHILADELPHIA — Researchers at the University of Pennsylvania’s Basser Center for BRCA at the Abramson Cancer … Read more

Black women less likely to receive guideline-concordant therapy for ovarian cancer

November 9, 2022 11:23 am

by Matthew Shinkle

Black women in the U.S. appeared less likely than white women to receive guideline-concordant treatment for ovarian cancer, according to a study published in Journal of the National Comprehensive Cancer Network.

Even among white women, the … Read more

Restoring the gut biome after antibiotics could lead to better outcomes for ovarian cancer patients

November 8, 2022 11:09 am

by Cleveland Clinic

Reassessing antibiotic dosage and type could improve survival rates in deadliest gynecologic malignancy, Cleveland Clinic research finds

Newswise — CLEVELAND – Antibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression … Read more

Ovarian cancer surveillance results in earlier diagnosis for women with faulty BRCA genes who want to defer surgery

November 1, 2022 4:17 pm

by British Medical Journal

Regularly monitoring women with faulty BRCA genes that make them highly susceptible to ovarian cancer results in earlier stage diagnosis in those who want to defer preventive surgery, finds research published online in the Journal of Read more

Eligibility Not Responsible for Under Representations in Cancer Clinical Trials

October 18, 2022 10:16 am

by Jessica Nye, PhD

Left image: Eligibility and opportunity for participation in cancer clinical trials was found to be similar across race, level of disadvantage, and residential area. Source: Getty Images

Eligibility was not found to drive disparities in clinical … Read more

Study could help recommend the best treatment for women with early-stage mucinous ovarian cancer

October 12, 2022 1:23 pm

by Emily Henderson, B.Sc.

A global study into mucinous ovarian cancer could help oncologists recommend the best treatment for women who are diagnosed early with the condition.

By looking down a microscope for two different ‘patterns of invasion’ – the … Read more

Identifying the Underlying Causes of Ovarian Cancer

October 6, 2022 1:48 pm

by Cedars-Sinai

New Studies Led by Cedars-Sinai Investigators Help Pinpoint Genetic Risk Factors Tied to Increased Risk of Ovarian Cancer and Suggest How to Better Identify Women Most At Risk

Image on left: Simon Gayther, PhD, professor of Biomedical Sciences, Read more

Pembrolizumab Plus Bevacizumab and Cyclophosphamide Shows Promising Efficacy, Tolerability in Recurrent Ovarian Cancer

September 26, 2022 9:49 am

by Megan Hollasch

Real-world data from a retrospective study showed that pembrolizumab combined with the anti-VEGF agent bevacizumab plus oral metronomic cyclophosphamide displayed minimal toxicity in a significant number of patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal Read more

Ovarian Cancer Detection Takes a Step Forward

September 12, 2022 1:45 pm

A new type of technology can capture stray ovarian cancer cells from a simple blood test and successfully predict cancer in people who have a lesion or cyst in the pelvic region, according to a new study by a Wilmot … Read more

Fertility Concerns a Significant Issue for Gynecologic Cancer Survivors

July 29, 2022 12:59 pm

by Jessica Nye, PhD

A systematic review found that fertility and parenthood were important and affected quality of life for young patients with gynecologic cancers; however, counseling and referral to fertility services is suboptimal. These findings were published in The Read more

Understanding the genetic testing-related information needs of ovarian cancer patients

July 29, 2022 11:45 am

Reviewed by Emily Henderson, B.Sc.

JMIR Publications recently published “Understanding the Information Needs of Patients With Ovarian Cancer Regarding Genetic Testing to Inform Intervention Design: Interview Study” in JMIR Cancer, which reported that experts in gynecological cancer care recommend that … Read more

Meta-Analysis Examines Link Between Aspirin Use and Ovarian Cancer Risk

July 28, 2022 10:32 am

by The ASCO Post Staff

Frequent aspirin use may be linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published by Hurwitz et al in the Journal of Clinical Oncology.

“Ovarian … Read more