Tag: Genetic Testing
Review Highlights the Need to Increase Germline BRCA Mutation Testing in Males
August 12, 2024 9:00 amby Jax DiEugenio
Although the risks of cancer developing in females harboring germline BRCA1or BRCA2 mutations are understood and have propelled genetic testing and preventative measures for this population, more work is required to amplify the rates of this … Read more
Study Finds Higher Rates of Hereditary Cancer Mutations in Minority Populations Missed by Current Screening Guidelines
July 24, 2024 9:00 amby IPM staff
A new study from the Mayo Clinic finds that current screening protocols fail to catch a significant number of individuals with genetic mutations linked to hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome, which increase … Read more
The best way to prevent this deadly cancer is to remove multiple organs. And I’m about to do it.
June 24, 2024 9:00 amClearity’s Perspective: This article is written by a daughter whose mother was diagnosed with advanced ovarian cancer. She shares the story of her mother’s diagnosis and treatment and how her family handled learning of her mother’s inheritable genetic condition. Clearity
Achieving High-Quality Care for Patients With Ovarian Cancer
June 10, 2024 9:00 amClearity’s Perspective: This article highlights that some people with ovarian cancer who live in certain geographic locations, like rural areas, may get treated at centers with less experience treating ovarian cancer and/or fewer resources to support whole-person needs. Clearity offers … Read more
Cancer Prevention Strategies Linked to Mortality Reduction in BRCA Carriers
February 29, 2024 9:00 amBy Mike Basset
Risk management strategies including bilateral salpingo-oophorectomy (BSO) for ovarian cancer and MRI surveillance for breast cancer were associated with a significant reduction in mortality for women with BRCA1/2 sequence variations, according to results from two cohort studies … Read more
Claudine Isaacs, MD, on the Limitations of At-Home Genetic Tests for Hereditary Breast/Ovarian Cancers More than 95% of BRCA1 or BRCA1 pathogenic variants would have been missed by DTC testing, largest such study showed
November 8, 2023 9:00 am By Mark Fuerst
Direct-to-consumer (DTC) genetic testing has limited use as a screening tool for identifying individuals at risk of hereditary breast or ovarian cancer, especially in those of non-Ashkenazi Jewish descent, researchers reported.
Most current DTC genetic tests evaluate … Read more
First Blood Test for Dozens of Hereditary Cancers Approved by FDA
October 2, 2023 9:00 amThe FDA has approved the first blood test that can help identify hundreds of potentially cancer-associated hereditary variants. The Invitae Common Hereditary Cancers Panel evaluates a blood sample to identify DNA variants in 47 genes associated with an elevated risk … Read more
Dr Rebecca Brooks Covers Ovarian Cancer Risk Factors, Preventive Measures
September 29, 2023 9:00 amBy Hayden E. Klein
For Ovarian Cancer Awareness Month in September, Rebecca Brooks, MD, talked to The American Journal of Managed Care® (AJMC®) about how genetics and family history play a large role in ovarian cancer … Read more
Clinical trial gives women with gene mutation power over disease
September 8, 2023 9:00 amShared by Norma Rabago
When Juana Padron, a 40-year-old mother of four, chose to have a genetic test, going against her friends and family’s advice was the last thing on her mind.
Padron’s aunt died from breast cancer, and she … Read more
Tumor Testing May Be Increasingly Useful in Ovarian Cancer
May 8, 2023 3:00 pmTesting tumors with next-generation sequencing in patients with ovarian cancer can provide teams insight into targetable mutations that may affect treatment decisions, although this approach is not the current standard of care for all patients, an expert said.
In an
Exome sequencing identifies cancer predisposition-gene carriers screening guidelines miss
April 19, 2023 12:55 pmby Jennifer Southall
Whole-exome sequencing identified carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome who, under current guidelines, would not have qualified for genetic testing, according to study results.
The findings, presented at American Association … Read more
Tailored Phone Calls Increased Rate of Genetic Testing, Counseling for Hereditary Cancer Risk
March 2, 2023 9:44 amby Alison Kanski
NEW YORK – Personalized phone discussions about genetic risk assessment increased the number of breast and ovarian cancer patients who got genetic testing or discussed their risk with a genetic counselor, a study from Rutgers Cancer Institute … Read more
Ovarian Cancer in Black and African American Communities
February 3, 2023 3:10 pmOvarian cancer outcomes are less positive for Black and African American persons compared to other communities, but the reasons why are not entirely clear. Anne Mette Buhl, PhD, Director of Science and Clinical Trials, from The Clearity Foundation, recently contributed … Read more
Melissa Frey, MD, on Disparities in Ovarian Cancer Genetic Testing
October 19, 2022 10:40 amby Mark L. Fuerst
Most people with a hereditary ovarian cancer syndrome are unaware of their underlying mutation, and the majority have not had genetic testing.
In a recent article in the ASCO Educational Book, Melissa Frey, MD, MS, … Read more
Identifying the Underlying Causes of Ovarian Cancer
October 6, 2022 1:48 pmby Cedars-Sinai
New Studies Led by Cedars-Sinai Investigators Help Pinpoint Genetic Risk Factors Tied to Increased Risk of Ovarian Cancer and Suggest How to Better Identify Women Most At Risk
Image on left: Simon Gayther, PhD, professor of Biomedical Sciences, … Read more
Study Finds Genetic Counseling for Breast, Ovarian Cancer Syndrome Did Not Significantly Increase with Clinician Support
August 15, 2022 11:11 amby Erin Hunter
Women at high risk for breast and ovarian cancer felt less worried and better informed with educational intervention, even if their attendance of genetic counseling did not significantly increase.
A new study shows that access to clinician
Understanding the genetic testing-related information needs of ovarian cancer patients
July 29, 2022 11:45 amReviewed by Emily Henderson, B.Sc.
JMIR Publications recently published “Understanding the Information Needs of Patients With Ovarian Cancer Regarding Genetic Testing to Inform Intervention Design: Interview Study” in JMIR Cancer, which reported that experts in gynecological cancer care recommend that … Read more
Key to detecting ovarian cancer early may be in the fallopian tubes
April 4, 2022 3:20 pmby Caren Begun
Tennis legend Chris Evert—known for her 18-time grand slam success in the sport—has made recent headlines after revealing an early-stage ovarian cancer diagnosis and speaking out to help others by sharing her personal experience.
According to the … Read more
BRCA Testing Underused in Women With Ovarian Cancer
January 14, 2022 9:00 amby M. Alexander Otto, MMS, PA
Despite unequivocal recommendations for universal germline BRCA testing in women with ovarian cancer, an analysis of a large commercial insurance database between 2008 and 2018 found that only about one third (33.9%) of such … Read more