Tag: Immunotherapy
‘Personalized’ Ovarian CA Vaccine May Prolong Survival
April 16, 2018 9:42 pmA novel cancer vaccine made from autologous whole-tumor and dendritic cells significantly improved survival in women with recurrent advanced epithelial ovarian cancer (EOC), given alone or in combination with standard immunomodulatory therapy, researchers found.
An international pilot study in 25 … Read more
New Immunotherapy Shows Promise Against Ovarian Cancer
April 10, 2018 8:57 pmOvarian cancer can be tough to beat, particularly if it returns after initial treatment, but new research offers a glimmer of hope.
One study found that a new targeted “immunotherapy” to treat ovarian cancer that has come back looked promising … Read more
SGO 2018: Immunotherapy/PARP Inhibitor Combination Produces Remissions in Ovarian Cancer
April 2, 2018 5:19 pmA combination of the immunotherapy pembrolizumab (Keytruda) and the DNA repair–blocking agent niraparib (Zejula) can be significantly more effective than either drug alone in women with hard-to-treat ovarian cancer, a phase I/II clinical trial led by Dana-Farber Cancer Institute researchers … Read more
SGO 2018: A Vaccine Shows Promise Against Ovarian Cancer
March 26, 2018 9:11 pmA vaccine derived from a patient’s tumor cells, which enhances T-cell targeting of cancer cells, has shown promise against ovarian cancer.
This outcome of a phase 1 clinical trial was reported at the Society of Gynecologic Oncology’s 2018 Annual Meeting … Read more
Doctors Said Immunotherapy Would Not Cure Her Cancer. They Were Wrong.
February 21, 2018 7:16 pmNo one expected the four young women to live much longer. They had an extremely rare, aggressive and fatal form of ovarian cancer. There was no standard treatment.
The women, strangers to one another living in different countries, asked their … Read more
Combinations May Be The Future Of Immunotherapy In Ovarian Cancer
January 12, 2018 10:27 pmTo date, trials testing the use of immunotherapy in the treatment of ovarian cancer yielded disappointing results. However, researchers are not giving up. Instead, they’re investigating to see if immunotherapy drugs – such as PD1 and PDL-1 inhibitors – can … Read more
Future Focus: Ovarian Cancer in 2018 and Beyond
December 14, 2017 3:49 pmOliver Dorigo, M.D., Ph.D., Associate Professor of Obstetrics and Gynecology (Oncology), Stanford University Medical Center, talks about the direction of research in the ovarian cancer field going into 2018 and beyond. He shares his excitement about trials that will further … Read more
Immunotherapy Has Big Potential In Ovarian Cancer Treatment
November 27, 2017 8:50 pmEarly studies are showing promise for immunotherapy agents such as checkpoint inhibitors in the treatment field of ovarian cancer, according to Jonathan Ledermann, M.D.
One such study is JAVELIN Ovarian 200, a study of Bavencio (avelumab) alone or in combination … Read more
What Is Immunotherapy? The Basics on These Cancer Treatments
August 23, 2017 2:55 pmSome of the most promising advances in cancer research in recent years involve treatments known as immunotherapy. These advances are spurring billions of dollars in investment by drug companies, and are leading to hundreds of clinical trials. Here are answers … Read more
Immunotherapy Treatment for Cancer: Hope or Hype?
June 9, 2017 3:52 pmBy: Annette McElhiney
As an avid reader of any and all material about cancer, my attention was grabbed by the article, “Hope and Hype Around Cancer Immunotherapy.”
Most of us are aware of the excitement currently generated by … Read more
Hope and Hype Around Cancer Immunotherapy
June 5, 2017 10:30 pmImmunotherapy treatments for cancer are having a moment.
Some hospitals and health care systems call it a “miracle in the making” and a “game-changer.” It’s a treatment approach that harnesses the body’s own immune system to target and attack a
… Read more
Immunotherapy Motolimod Fails to Improve Survival in Ovarian Cancer
March 24, 2017 4:29 amThe addition of the immune therapy motolimod to pegylated liposomal doxorubicin (PLD) failed to improve overall survival among women with recurrent epithelial ovarian carcinoma in a randomized phase II trial. There was a survival advantage, however, specifically in patients who … Read more
Combination Of Chemotherapy And Immunotherapy May Be Effective
June 8, 2016 7:04 pmInside each ovarian tumor, there are good cells and bad cells. A new paper explains their roles: The bad cells are fibroblasts. They work to block chemotherapy, which is why nearly every woman with ovarian cancer becomes resistant to treatment. … Read more